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hematology causes algorithm hemolytic classification extravascular intravascular platelets aiha autoimmune bilirubinemia blood dermatology disorders hodgkins jaundice lymphoma management markers nonpalpable
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... known as atypical HUS ... anemia" • HELLP ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Diagnosis Secondary ... malignancies • Anemia ... iron deficiency, hemolysis ... #hematology #secondary
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... • Infection/Sepsis ... #Platelets #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis ... Differential #Diagnosis ... #Table #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... anemia • ... MAHA (TTP, DIC, HUS ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... #Anemia #Differential ... #workup #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology ... #Diagnosis #Algorithm
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • MAHA: TTP, HUS ... #Anemia #Differential ... #Diagnosis #causes
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