17 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... known as atypical HUS ... anemia" • HELLP ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... coagulation (DIC) - HELLP ... uremic syndrome (HUS ... #differential # ... #anemia
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
Causes of AKI in ... Progression • HUS ... • HELLP • Lupus ... Nephritis • AFLP ... #table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS ... of Pregnancy (AFLP ... (Hemolysis, Elevated ... child * Severe cases ... #table #comparison
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... anemia • ... MAHA (TTP, DIC, HUS ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • MAHA: TTP, HUS ... , DIC, HELLP, AS ... #Anemia #Differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Wilsons, Pregnancy - AFLP ... , HELLP • Moderate ... Drugs, Infection, Sepsis ... Algorithm #diagnosis #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... thrombocytopenia - DIC, TTP, HELLP ... , HUS, aHUS, mechanical ... #Anemia #Differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Pregnancy - AFLP ... , HELLP Moderate ... Drugs • TPN • Sepsis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
(Hemolysis, Elevated ... child * Severe cases ... #AFLP #Obstetrics ... #OBGyn #Hematology ... Diagnosis #Comparison #Table