12 results
diagnosis algorithm causes transaminitis blood intravascular liver oncology product reactions apml bilirubinemia chemistry classification coagulation dic differentiation disseminated elevated extravascular
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Drug-induced AIHA - Abnormal ... MAHA (TTP, DIC, HUS ... Extravascular #Differential ... Algorithm #Causes #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Drugs, Infection, Sepsis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... — Normal Bile Ducts ... Drugs • TPN • Sepsis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Levels: > 50x normal ... - Hemolysis, NASH ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... Blood Smear ↑ abnormal ... #Differential # ... Diagnosis #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Bilirubin: RBC (hemolysis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
history of trauma, sepsis ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... causes #treatment #management ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Occurs between 0-6 hrs ... Can lead to sepsis ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Hemolysis on labs ... Occurs between 0-6 hrs ... Can lead to sepsis ... Transfusions #diagnosis #management ... #hematology #reactions
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