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Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Macroangiopathic, Microangiopathic ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Anemia - Hemolysis Diagnostic Algorithm Autoimmune hemolytic anemia Microangiopathic hemolytic anemia Probable thalassemia Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... anemia Microangiopathic ... hemolytic anemia ... #hematology #diagnosis ... #differential #
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... Drug-induced thrombotic microangiopathy ... anemia" • HELLP ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
hemolytic anemia ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... (TMA) - Differential ... Diagnosis Table ... #TMA #hematology ... #differential #
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Schistocytes DAT(-) → Microangiopathic ... hemolytic anemia ... (TTP, HUS, DIC, ... #Anemia #Differential
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Environment - Microangiopathic ... #Anemia #Differential ... Diagnosis #Causes #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... Fragments • Microangiopathic ... Hemolytic Anemias ... #Differential #
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... Often hard to differentiate ... Comparison #Diagnosis #Table ... #Hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Schistocytes: Microangiopathic ... hemolytic anemia ... DIC, TTP, HUS) ... Microspherocytes: Autoimmune hemolytic ... Smear #Analysis #hematology
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