22 results
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Phosphate Binders ... and metal-free binder ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... since they are not able ... aluminum-based phosphate binder ... calcium-based phosphate binders ... Only* #CKD #Nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
desired serum K ... also binds magnesium ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... Kayexelate #Comparison #Table ... #HyperKalemia #Nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
extracellular K+ ... Tissue injury • Hemolysis ... acute iatrogenic K+ ... injection Decreased K+ ... blockers - MCW Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... • Digoxin • K ... cell lysis: - Hemolysis ... K supplement 3 ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... • Digoxin • K ... cell lysis: - Hemolysis ... K supplement 3 ... potassium #high #nephrology
Sickle Cell Disease (SCD) Nephropathy
 • Cortical Manifestations
    - Main issue: Hemolysis-associated endothelial
- Main issue: Hemolysis-associated ... - Impaired K ... #differential #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
• Medications: K+ ... injury, ischemia, hemolysis ... Pseudohyperkalemia - hemolysis ... Elimination (see Table ... Treatment #potassium #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... edgarvlermamd - Nephrology ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #Nephrology