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diagnosis symptoms differential lupus erythematosus manifestations neurology ophthalmology systemic acute algorithm alzheimersdisease bulimianervosa centralretinalartery chronic cll closedangle cord crao crisis
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... / Symptoms / Complications ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... column) • Late complication ... minor trauma #AnkylosingSpondylitis ... #pathophysiology ... #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Fits, Hemiplegia, Ataxia ... pain (20%) Renal disease ... Thrombocytopenia #Lupus #SLE ... erythematosus #signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Collapse: • Pathophysiology ... → Syncope • Signs ... electrolyte losses - Ataxia ... muscle function, Ataxia ... differential #diagnosis #causes
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Sickle-cell disease ... Sickle cell disease ... The underlying pathophysiology ... ischaemia. 2) Aplasia ... Crisis #Features #Signs
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... often- Sensory ataxia ... Non-compressive Spinal Cord Causes ... Sarcoidosis, Behcet disease ... - SLE, Scleroderma
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... GCA, SLE, GPA) - ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... cells can indicate disease ... Pure red cell aplasia ... kinase (BTK) Complications
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