46 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Supportive with treatment ... #SickleCell #Disease ... Hepatobiliary #hepatology ... #hepatitis #differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Blood Loss • Acute ... Anemia of Chronic Disease ... Classification #Approach #Differential ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Thrombocytosis #Platelets #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Algorithm #Causes #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... associated with the BCR-ABL1 ... translocation • Acute ... thrombocythemia • Acute ... Colitis and Crohn’s Disease
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
and less common diseases ... diagnosis and treatment ... Cogan syndrome • Acute ... BEE #Syndromes #neurology ... #inflammatory #differential
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... Minimal change disease ... malignancies Treatment ... Cancer #Oncology #Differential
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... - Acute Bleeding ... #treatment #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential