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diagnosis aki nephrology differential management algorithm classification hepatology aclf acutekidneyinjury cancer causes chronic cirrhosis dehydrogenase dili diuresis diuretics druginduced elevated
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... • Glomerular disease ... #Kidney #Injury ... Classification #diagnosis #nephrology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... Circulation Failure Kidney ... Injury (DILI)
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
Kidney Injury ... • Drug induced acute ... kidney injury is ... • Treatment includes ... Vancomycin #AKI #pharmacology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... LC deposition disease ... Minimal change disease ... malignancies Treatment ... #Kidney #Injury
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Skin involvement, Kidney ... non-essential drug/HDS treatments ... disease, Hepatic ... dechallenge • Acute
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Torsemide) • Acute ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... Treat underlying liver ... disease, ? ... the underlying disease ... #Kidney #Injury
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... - TTE/liver fxn? ... - Pre-renal disease ... AcuteKidneyInjury #AKI #Nephrology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... , muscle, liver, ... and kidney • ... : • Early acute ... hepatitis • Acute
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