15 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Kidney Failure ... #Hepatology #gastroenterology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... hepatic crisis: ... Supportive with treatment ... liver failure ... Hepatobiliary #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... • Hematologic ... malignancies Treatment ... depletion • Hepatic
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
kidney disease, ... kidney disease, ... kidney disease ... kidney disease ... Tolvaptan) • Treatment
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... of cholestatic disease ... replaced by non-hepatic ... > 2 • NASH, Chronic ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury: • Hepatic ... • Hepatic artery ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
/ Liver Failure ... —100-fold with acute ... liver failure; ... liver disease, ... #Hepatology #Laboratory
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
• Anemia of chronic ... kidney disease, ... • Bone marrow failure ... Index > 3: • Acute ... Production #Index #hematology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Hepatic Encephalopathy ... other causes of neurologic ... over course of disease ... LizzieAbyMD #Hepatic ... #hepatology