29 results
Causes of Encephalopathy - Differential Diagnosis Algorithm
Hyperacute:
 - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
- Differential Diagnosis ... Acute: - Primary ... Inflammatory (Acute ... - Systemic: Chronic ... Autoimmune, OSA Chronic
Interpretation of Hepatitis B Serologies 
HBsAg - HBcAb (total) - HBcAb (IgM) - HBsAb
Susceptible to HBV
Immune
to HBV vaccine Acute ... HBV Chronic HBV ... acute infection ... HepBVirus #Serologies #serology ... #diagnosis #hepatology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
- Acute B1 (Thiamine ... • Chronic alcoholism ... Anorexia nervosa Treatment ... • A prompt treatment ... #Management #neurology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Coagulation Failure Infections ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
- Anti-HBe - Acute ... of cases) - Acute ... less commonly, infection ... Interpretation #diagnosis ... #laboratory #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... : Chronic infections ... #Differential #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Myelofibrosis Infectious ... : • Acute or Chronic ... effect following treatment ... Algorithm #Causes #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... dechallenge • Acute ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 20x normal - Acute ... 10-20x normal - Infection ... 5-10x normal - Chronic ... #hepatology #LFTs ... #differential #diagnosis
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... Disorders: • Chronic ... associated with the BCR-ABL1 ... translocation • Acute ... #causes #hematology