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diagnosis differential management cirrhosis classification product table algorithm alkaline alkphos allergy alp anemia artificial astalt basophilia basophils biliary chemistry cholangitis
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
blood is a liquid ... Blood saves lives ... unnecessary and cause ... Transfusions are ... #Thresholds #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... Defects, Drugs, Liver ... - Peripheral Blood ... Differential #Diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... of high parity blood ... without other cause ... • Pathophysiology ... #Reactions #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... mitochondria (mAST ... initial insult Bilirubin ... #Hepatology #Pathophysiology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... prosthetic valve • Transfusion ... reactions ex. ... classification #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... function similarly to mast ... during an allergic reaction ... Or Inflammatory Reactions ... #hematology #basophils
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies bind ... to mast cells via ... destruction after transfusion ... Classification #Pathophysiology ... Allergy #Diagnosis #Reactions
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... week • Direct bilirubin ... Elevation: • Bilirubin ... intestines, white blood ... diagnosis #algorithm #hepatology
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