55 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... #management #treatment
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... and treatment can ... Inflammatory causes ... • Systemic lupus ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... #Diagnosis #Management ... #Summary #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... lupus. ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... LAC) • Sjogren Syndrome ... • Scleroderma (Systemic ... #diagnosis #associations ... #table
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
- Differential Diagnosis ... Stevens-Johnson Syndrome ... necrolysis - Systemic ... lupus erythematosus ... #Algorithm #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... months to years) Systemic ... sle #comparison #table ... #rheumatology # ... diagnosis #management