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diagnosis differential hematology causes management oncology leukemia workup disorders fever hiv infectiousdiseases lymphocytic mouth oral syndrome thrombocytosis abg acid acidbase
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... extramedullary disease ... pain, bleeding, infections ... - infiltrates (anemia ... #Leukemia #Hematology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the ... Evaluation of Chronic ... Parasitic infections ... Systemic disease ... #algorithm #workup
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... of Chronic Disease ... of Chronic Disease ... , Chronic Infection ... #Causes #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... diarrhea • ... autoimmune hemolytic anemia ... Malignancies • Chronic
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
kidney disease, ... (e.g. cancer, infection ... defects (e.g. sickle cell ... ), Infections, Hypersplenism ... Production #Index #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... : • Acute or Chronic ... disorders • Celiac disease ... Iron deficiency anemia ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... cells can indicate disease ... • Neutropenia, anemia ... #Chronic #Lymphocytic
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Encapsulated Bacteria Cell ... • Periodontal Disease ... Bronchitis • Chronic ... Diarrhea • Giardia ... #Causes #Hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Infections 2. ... abdominal pain, diarrhea ... , Chronic spontaneous ... urticaria, Chronic ... doi: 10.1111/all
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Differential Diagnosis Algorithm ... • Burns • Diarrhea ... Smoking, Snoring Chronic ... Sleep Apnea • Chronic ... #Causes #Hematology
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