10 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Anemia • Toxic Damage ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... - APLS • Acute ... Scurvy - Actinic damage ... Associated - SLE ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... disease Tissue Damage ... following EtOH induced thrombocytopenia ... #Causes #Hematology
Atypical HUS - Hemolytic Uremic Syndrome
Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
Hemolytic Uremic Syndrome ... autoimmune like SLE ... present with anemia, thrombocytopenia ... evidence of end organ damage ... which has more acute
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Mechanisms: • Direct Damage ... infections/fevers • Thrombocytopenia ... and petechiae Causes ... : - Genetic lesions ... Anemia #oncology #hematology
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... , vomiting, diarrhea ... 14%), in which case ... Mild anemia • Thrombocytopenia ... • New onset SLE
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... infiltrates (anemia, thrombocytopenia ... • Tumor lysis syndrome ... #Leukemia #Hematology
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... #diagnosis #dermatology ... Acute effects of ... Beane Freeman LE ... Genetic determinants
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
PATHOPHYSIOLOGY: The exact cause ... , diarrhea, or joint ... permanent organ damage ... neutropenia (CyN) This genetic ... It causes the absolute
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... Familial) HLH: - Genetic ... Cytopenias (anemia, thrombocytopenia ... • Tissue damage ... Diagnosis #Management #Hematology