10 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... Hypersplenism • Secondary ... RA, SLE, PRV, Chronic ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... : ITP • Secondary ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... There are primary ... and secondary TMA ... catastrophic APS, SRC, SLE ... Microangiopathy #TMAs #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... some time, let’s see ... Differential #Diagnosis #Algorithm ... #workup #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... • Infectious diarrhea ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... + distinctive primary ... bone marrow and secondary ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
NO underlying primary ... or secondary immune ... Autoimmune (Sjogren, SLE ... ICL #diagnosis #hematology ... #Differential #Causes
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
HLH) Treatment Primary ... transplantation Secondary ... Options for severe cases ... HLH #Treatment #management ... #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... Types of HLH • Primary ... STX11, STXBP2 • Secondary ... #Hematology #HemeOnc