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diagnosis differential management oncology classification lupus systemic anemia cll comparison dermatology erythematosus lymphocytic naildisorders polycythemia secondary summary table thrombocytosis vasculitis
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Lung, Bladder, Colon ... • Chronic myelogenous ... vera Acute Leukemia ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia ... : • Acute or Chronic ... • Rheumatic disorders ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Age > 50 • Chronic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... hemorrhage) • Chronic ... inflammatory disorders ... myeloid leukemia ... #hematology #secondary
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Leukemia, Tumour ... Autoimmune • ITP • SLE ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... • Lymphoma • Leukemia ... Myeloproliferative disorders ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Myeloproliferative Disorders ... : • Chronic myeloid ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
(VIII is most common ... Malignancy, Autoimmune disorders ... RA, SLE), Post-partum ... promyelocytic leukemia ... comparison #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... involvement CML (Chronic ... -> AML: Blast crises ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Epidemiology: • Most common ... lymphoproliferative disorders ... #CLL #Chronic ... workup #oncology #hematology
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