19 results
Adverse Effects of NSAIDs
Prostaglandins decreased
 - Gastric mucosal damage with ulcer formation, bleeding, and perforation
 -
wound healing, diarrhea ... effect #NSAIDs #AdverseEffects ... #SideEffects #Pharmacology
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
#IBSD #IBS #Diarrhea ... Bowel #Syndrome #pharmacology ... #table #comparison
Diarrhea Workup and Management Algorithm in Transplant Patients
First Tier Microbiologic-Testing:
1. C. difficile PCR (Stool)
2. CMV qPCR
Diarrhea Workup ... Ova and Parasite ... testing negative and diarrhea ... Adjust IS medications ... malabsorption #Diarrhea
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... Nausea, vomiting, diarrhea ... Tranexamic #Acid #Indications ... #Pharmacology #
Irritable Bowel Syndrome (IBS) Treatment Options
Amitiza (Lubiprostone)
Antidepressants: Celexa, Wellbutrin, Prozac, Paxil, Nortriptyline, and Zoloft
Bentyl (Dicyclomine)
Creon
Ducolax
Imodium, Maalox,
syndrome #ibs #diarrhea ... constipation #management #pharmacology ... #table
Intern Pocket Cards - Inpatient Anti-Emetics Guide
Serotonin antagonists:
 • Ondansetron (Zofran), Granisetron (Kytril, Sancuso) - Headache,
constipation, drowsiness, diarrhea ... antiemetics #vomiting #medications ... #pharmacology # ... table #agents #internship
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
intolerance nausea, diarrhea ... recommended with other medications ... Benefits #Lupus #pharmacology ... #adverseeffects
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
constipation, diarrhea ... constipation, diarrhea ... #Hyperkalemia #medications ... #pharmacology # ... table #comparison
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
losses - Chronic diarrhea ... Renal Loses - Medications ... Low #Magnesium #Table
Pearls for Treatment of Alcohol Use Disorder

First-line pharmacotherapies for moderate to severe AUD include naltrexone and
pain, nausea, and diarrhea ... Screening #Addiction #Medications ... #Pharmacology