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diagnosis differential erythematosus lupus autoimmune myositis pain sclerosis vasculitis workup algorithm antibodies antinuclear arthritis autoantibodies behcet chronic classification cll conditions
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... Internal Organs: • Joint ... Ann Marie Kumfer ... #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... Musculoskeletal: joint ... #SSc #rheumatology ... #diagnosis #signs
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... phenomenon (20%) Joints ... Arthritis in small joints ... #signs #symptoms ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Neurologic system ... Telangiectasia • Scleroderma ... Thickened skin • Scleroderma ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... #Systemic #Lupus ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... , holster sign, ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... - Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Arthritis: • Joint ... arthropathy • 90% joints ... Induced Lupus: • Symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... and signs below ... Behcet disease - SLE ... , Scleroderma, Systemic ... response LMN Symptoms
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