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diagnosis differential erythematosus lupus vasculitis algorithm ana antibodies antinuclear autoantibodies chronic classification cll conditions cord diffuse disorders extrarticular hematology leukemia
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... Internal Organs: • Joint ... #Sclerosis #Scleroderma ... #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... Musculoskeletal: joint ... #Sclerosis #Scleroderma ... #SSc #rheumatology ... #workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
sclerosis or scleroderma ... sclerosis/scleroderma ... sclerosis/scleroderma ... ), Systemic sclerosis ... ), Systemic Sclerosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... phenomenon (20%) Joints ... Arthritis in small joints ... #signs #symptoms ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... • Scleritis ... Telangiectasia • Scleroderma ... Thickened skin • Scleroderma ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... : - Multiple sclerosis ... Behcet disease - SLE ... , Scleroderma, Systemic ... sclerosis - MCTD
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Diffuse Systemic ... Sclerosis (Scleroderma ... overgrowth -> diarrhea ... pathophysiology #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... , particularly scleritis ... purpura: Strong sign ... Differential #Diagnosis #Rheumatology
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