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diagnosis signs differential symptoms workup syndrome dermatomyositis disease algorithm autoimmune blood dermatology erythematosus lupus malignant myositis product sle transfusion treatment
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... - Interstitial lung ... Dermatomyositis #Diagnosis #Rheumatology
Transfusion Reactions - Summary Cheatsheet • Hemolytic Reaction • Febrile Reactions • Transfusion Related Acute Lung
Transfusion Reactions ... • Febrile Reactions ... Related Acute Lung ... #diagnosis #management ... #hematology #complications
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... heliotrope rash, Shaw sign ... , holster sign, ... Myositis #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... effusion, Restrictive lung ... joints Nervous system ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... allergy, drug reaction ... organ-specific signs ... Differential #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Seen in: • Systemic ... Central nervous system ... rash) • Heart, lung ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... Lupusreference #SLE #Systemic ... autoantibodies #signs ... #differential #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
female, asian • Systemic ... biliary, renal, lung ... increased IgG4+ cells ... Disease #diagnosis #management ... workup #treatment #rheumatology
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
aka. cancerous cells ... from systemic locations ... • Lung. thvroid ... Signs/Symptoms: ... Interrupted periosteal reaction
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