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differential management rheumatology abnormal aflp algorithm aptt bleeding bruising comparison dermatomyositis hellp obstetrics pregnancy prolonged pt table thrombocytopenia ttphus antimda5
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Iatrogenic) • Liver ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... deficiency • Liver ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Causes include : ... • Reduced liver ... #diagnosis #differential ... #hematology #coagulation
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
malnutrition) Blue ... discoloration) • Liver ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Syndrome, Ischemic Liver ... intravascular coagulation ... and other causes ... pathophysiology #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Periorbital heliotrope (blue-purple ... disease and ILD • Liver ... Liver biopsies show ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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