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diagnosis management hematology differential causes anemia algorithm oncology neurology clinical rheumatology hemolytic signs symptoms bloodsmear cardiology infectiousdiseases leukemia nutrition pancytopenia
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Marrow Failure Syndromes ... Acquired Aplastic ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes
Causes of Aplastic Anemia #Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Constitutional Syndromes ... Constitutional Syndromes ... anemia Treatment
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic Anemia ... (AIHA) Pathophysiology ... or negative - Smear ... C3 positive - Smear ... #Pathophysiology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Normochromic RBCs on Smear ... Deficiency • Aplastic ... Anemia • Anemia ... Spherocytes on Smear
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... Treatment: • Consider ... Medicine @SCVMCMed #Aplastic ... #management #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Non-lmmune: • HELLP Syndrome
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... C3d • Blood smear ... Autoimmune #Hemolytic #Anemia ... diagnosis #management #treatment
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