10 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
and Intravascular ... Diagnosis Algorithm ... Extravascular ... Intravascular ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Intravascular vs ... Extravascular Causes ... #Hemolytic #Intravascular ... #Extravascular ... #hematology #anemia
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular ... #key #diagnosis ... #differential #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Algorithm Decreased ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... • Early Iron Deficiency ... #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Diagnosis Algorithm ... (not extravascular ... ) hemolysis, Intensive ... #Diagnosis #Algorithm ... #ferritin #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... #hematology #microscopy ... #atlas #nomenclature
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #Diagnosis #Algorithm ... #workup #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... causing intravascular ... hemolysis on rewarming ... #anemia #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... . sickle cell anemia ... Production #Index #hematology ... #diagnosis #calculation
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
+Organomegaly+↑RBC ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology