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Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... : • Hypovolemia ... Neurogenic bladder • Bilateral ... Diagnosis #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
(AKI) in Patients ... Solid tumors • Secondary ... Cisplatin • ATN ... #Differential # ... Classification #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Pre-Renal: • Hypovolemia ... C3/C4, Other • ATN ... Diagnosis #nephrology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Hypertension - Differential ... HTN • Onset < ... Nephritic syndrome • AKI ... Liddle's syndrome • Bilateral ... #Secondary #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... (AKI) - Differential ... blood volume • Hypovolemia ... interstitium • ATN ... #AKI #Differential
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
to Acute Kidney Injury ... Cl/urea/protein/Cr ... Liano 1996) - ATN ... #Nephrology #Diagnosis ... Algorithm #Causes #Differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
of Acute Kidney Injury ... AKI - Differential ... nephropathy • Secondary ... /Necrosis (ATN) ... #Diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... declines > ALT) • AKI ... : BUN/Cr ↑ • Aldolase ... + myoglobin AKI ... or ATN 6.
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup and Differential ... or acute kidney injury ... most pts have HTN ... Neurologic disorders