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differential hyperkalemia hematology management potassium algorithm high nephrology anemia hba1c product reactions acute bilirubin blanching bruise coagulation congenital critical deficiency
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Content • RBC Transfusions ... turnover • Acute blood ... loss • Hemolytic ... #Decrease #Diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... #diagnosis #management
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... • Peripheral blood ... disease, drugs, transfusions ... #Differential #Diagnosis ... #Algorithm #causes
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... dietary intake • Blood ... transfusion • ... of injection Decreased
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... Crush injury • Blood ... Blood transfusion ... #differential #diagnosis ... #causes #potassium
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... Mild-to-moderate decrease ... in most cases; ... of Peripheral blood
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... Crush injury • Blood ... Blood transfusion ... #differential #diagnosis ... #causes #potassium
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... Potassium-rich diet • Blood ... transfusion • ... Tumor lysis/hemolysis
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... - Differential Diagnosis ... Algorithm • Blood ... Intravascular hemolysis ... MALABSORPTION • Decreased
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