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diagnosis differential hyperkalemia potassium hematology high management algorithm congenital dm2 elevated elevation false gastroenterology hba1c hemorrhage hepatology hgba1c hyperbilirubinemia ich
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... turnover • Acute blood ... loss • Hemolytic
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Tissue injury • Hemolysis ... dietary intake • Blood ... transfusion • ... of injection Decreased ... blockers - MCW Nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... transfusion • ... Blood transfusion ... differential #diagnosis #causes ... potassium #high #nephrology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... of Peripheral blood ... anemia Indirect bilirubin
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... transfusion • ... Blood transfusion ... differential #diagnosis #causes ... potassium #high #nephrology
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Diagnostic algorithm Decreased ... Potassium-rich diet • Blood ... transfusion • ... Tumor lysis/hemolysis ... Diagnosis #algorithm #nephrology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... patients have an increase ... in the blood
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology ICH Management: 1. Manage Blood Pressure •
) because they increase ... cerebral blood ... consider platelet transfusion ... = dilated BV = raises ... Pathophysiology #neurology
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... Potassium-containing drugs - Transfusion ... of aged blood ... - Hemolysis (in ... tissue necrosis Decreased
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