23 results
diagnosis differential hematology algorithm hyperkalemia elevation hba1c hemolysis management reactions @dharsaty abnormal acidosis allergy approach blood color comparison conjugated deficiency
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Content • RBC Transfusions ... blood loss • Hemolytic ... anemia • Splenomegaly ... #Decrease #Diagnosis
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... autoimmune (most of the causes ... , hemolytic transfusion ... #Classification
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... HUS) • Other: Transfusion ... implicated) - Transfusion ... Extravascular #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... → Sickle Cell anemia ... disease, drugs, transfusions ... anemia (TTP, HUS ... Diagnosis #Algorithm #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... Microangiopathic Hemolytic
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... prosthetic valve • Transfusion ... #Anemia #Differential ... #classification
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Hemolysis on labs ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... result in severe anemia ... Platelet count - Decreased ... anemia Indirect
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... • Bleeding • Hemolysis ... #MCV #Classification ... Diagnosis #Algorithm #Causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
combination of: Decreased ... Hypochromic RBCs Decreased ... Production - Normal / Decreased ... #Classification ... Diagnosis #Algorithm #Causes
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