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diagnosis differential hematology algorithm hyperkalemia management potassium nephrology pathophysiology anemia classes high cardiology criticalcare workup acidosis antiarrhythmics deficiency elevation endocrinology
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Reduction == Increase ... blood loss • Hemolytic ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... autoimmune (most of the causes ... , hemolytic transfusion ... #Classification
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Hemolysis on labs ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Infiltration - Increased ... Bleed • Hemolysis
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Differential Diagnosis Increased ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... udaygulati #Hemolytic ... #classification
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... - Transfusion ... hypoperfusion Increased ... Blood transfusion ... differential #diagnosis #causes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... nucleated RBCs, and decreased ... hematuria (without casts
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Diagnostic algorithm Decreased ... failure • Drugs Increased ... diet • Blood transfusion ... • Tumor lysis/hemolysis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... - Transfusion ... hypoperfusion Increased ... Blood transfusion ... differential #diagnosis #causes
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