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diagnosis differential management algorithm anemia hepatology bilirubin bilirubinemia blood bundle checklist coagulation congenital deficiency dic disseminated dm2 elevation false folate
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Reduction == Increase ... blood loss • Hemolytic ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Infiltration - Increased ... #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Differential Diagnosis Increased ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... nucleated RBCs, and decreased ... Diagnosis #Workup #Hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Hyperbilirubinemia Increased ... Production • Hemolysis ... • Hematoma Decreased ... Rifampin) Decreased ... Diagnosis #Algorithm #Causes
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... pregnant have hemolytic ... folate that can cause ... anticonvulsants lead to increase ... differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Treat primary cause ... Cryoprecipitate to increase ... hydration • RBC transfusion ... treatment #management #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... patients have an increase ... recessive disorder • Increase
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... characterized by a decrease ... However, these thresholds ... involves disorders of increased ... These causes could
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