42 results
diagnosis differential hematology algorithm anemia hyperkalemia management potassium endocrinology high nephrology classification coagulation intravascular aptt blood extravascular folate folicacid hba1c
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... -12, or folate deficiency ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... • Early Iron Deficiency
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... implicated) - Transfusion ... G6PD deficiency) ... Extravascular #Causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... DAT (-) → G6PD Deficiency ... Immune mediated hemolysis ... disease, drugs, transfusions ... Diagnosis #Algorithm #causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... Defects • G6PD deficiency ... • PK deficiency ... Diagnosis #Algorithm #Causes
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... - Transfusion ... paralysis - Insulin deficiency ... Mineralocorticoid deficiency ... differential #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... - Transfusion ... paralysis - Insulin deficiency ... Mineralocorticoid deficiency ... differential #diagnosis #causes
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Abnormal Lipid Profiles ... Hypothyroidism Decreased ... • Apo-A1 Deficiency ... • Familial LPL Deficiency ... #Dyslipidemia #Abnormal
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