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Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... think of immune hemolysis ... IVIG-mediated hemolysis ... , hemolytic transfusion ... #Differential #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Intravascular Hemolysis ... Microangiopathic hemolytic ... purpura (TTP), Hemolytic ... Extravascular Hemolysis
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Immune mediated hemolysis ... Microangiopathic hemolytic ... UnremarkableLab #Hemolytic ... #Algorithm #causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Content • RBC Transfusions ... blood loss • Hemolytic ... Effect • RBC Transfusions ... #Decrease #Diagnosis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... haptogbbulin #Hemolysis ... #Hemolytic #Anemia ... #Differential #Causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... - Febrile Non-Hemolytic ... - Acute Hemolytic ... Hemolysis on labs ... - Delayed Hemolytic
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... immune-complex hemolytic ... malformations #Hemolysis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... reticulocytes • Hemolysis ... 2) LOOK FOR a cause ... Antibody #Autoimmune #Hemolytic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... Microangiopathic Hemolytic
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... • Acute Hemolytic ... Hemolysis on labs ... etc) • Delayed Hemolytic ... , fever, minor hemolysis
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