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differential hematology hyperkalemia anemia algorithm management potassium classification comparison nephrology reactions table thrombocytopenia aflp blood hellp intravascular obstetrics pregnancy product
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Hypertriglyceridemia • Uremia High ... blood loss • Hemolytic ... #Decrease #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... HUS) • Other: Transfusion ... Extravascular #Causes ... #hematology #anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... High mortality. ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... High mortality. ... #diagnosis #management ... #hematology #reactions
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... Algorithm Decreased ... WBCs - Decreased ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... prosthetic valve • Transfusion ... udaygulati #Hemolytic ... #hematology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... glycosides • High ... intake • Blood transfusion ... of injection Decreased
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... phlebotomy High ... #differential #diagnosis ... #causes #potassium ... #high #nephrology
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... diet • Blood transfusion ... • Tumor lysis/hemolysis ... Normal, Renin High
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... Mild-to-moderate decrease ... in most cases; ... #Workup #Hematology
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