10 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... • Asplenia Laboratory ... Content • RBC Transfusions ... blood loss • Hemolytic ... HbA1c #HgbA1c #Laboratory
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Hemolysis on labs ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... nucleated RBCs, and decreased
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... Differential #Diagnosis #Causes
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
Insulin Deficiency Decreased ... Hyperbilirubinemia • Hemolysis ... Diagnosis #Algorithm #endocrinology ... #causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
incompatible blood transfusion ... venipuncture sites Laboratory ... Treat primary cause ... hydration • RBC transfusion ... Coagulation #diagnosis #causes
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
Laboratory Evaluation ... high; in some cases ... high; increased; decreased ... sedimentation rate normal; decreased ... differential #diagnosis #endocrinology
Causes of Hypocalcemia - Differential Diagnosis
Decreased calcium absorption
 • Vitamin D deficiency
    -
Causes of Hypocalcemia ... deficiency - Decreased ... +] • Massive transfusions ... Differential #Diagnosis #Causes ... #endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
aldosterone - Low in cases ... onset, there is an increase ... will produce an increase ... Insufficiency #Evaluation #laboratory ... diagnosis #testing #endocrinology
Causes of Hyperkalemia
Pseudohyperkalemia
 - Tourniquet use
 - Hemolysis (in vitro)
 - Leukocytosis
 - Thrombocytosis
Intra- to extracellular
Causes of Hyperkalemia ... Tourniquet use - Hemolysis ... Potassium-containing drugs - Transfusion ... aged blood - Hemolysis ... tissue necrosis Decreased