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diagnosis differential hyperkalemia anemia management hemolysis high intravascular nephrology potassium product rheumatology bilirubin classification coagulation comparison congenital dermatology dic disseminated
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Thresholds in Critical ... blood is a liquid ... Blood saves lives ... unnecessary and cause ... #Thresholds #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... Transfusion Reaction ... Transfusion Reaction ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Transfusion Reaction ... Transfusion Reaction ... Transfusion Reaction ... diagnosis #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... reaction, Paroxysmal ... reaction • Intrinsic ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... turnover • Acute blood ... loss • Hemolytic
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... reactions Common ... reaction - Tumor ... Blood transfusion ... differential #diagnosis #causes
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... prosthetic valve • Transfusion ... reactions ex. ... udaygulati #Hemolytic ... classification #hematology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... reactions Common ... reaction - Tumor ... Blood transfusion ... differential #diagnosis #causes
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... - Peripheral Blood ... Differential #Diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology
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