9 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Hypertriglyceridemia • Uremia High ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... High mortality. ... diagnosis #management #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... , spider/snake bites ... prosthetic valve • Transfusion ... udaygulati #Hemolytic ... classification #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... High mortality. ... more likely to cause ... diagnosis #management #hematology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... glycosides • High ... intake • Blood transfusion ... of injection Decreased
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
falsely high Hgb ... Hemolysis causes ... PCV to decrease ... PCV and MCV to decrease ... Echinocytes #BurrCells #Bite
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... Excretion into Bile ... Congenital #bilirubin #hepatology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... characterized by a decrease ... However, these thresholds ... These causes could ... thalassemia trait & high
Invasive Fungal Infection (IFI)

Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
with neutropenia, hematologic ... (most frequent cause ... rare fungi in high-risk ... Symptoms vary by site ... significantly increase