38 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Thresholds in Critical ... unnecessary and cause ... Transfusions should ... Transfusions are ... #Thresholds #Hematology
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Hypertriglyceridemia • Uremia High ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... implicated) - Transfusion ... Extravascular #Causes ... differential #diagnosis #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... High mortality. ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... High mortality. ... more likely to cause ... diagnosis #management #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... udaygulati #Hemolytic ... classification #hematology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... glycosides • High ... intake • Blood transfusion ... of injection Decreased
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... phlebotomy High ... - Transfusion ... differential #diagnosis #causes ... #potassium #high
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Basic labs for decreased ... liver disease, decrease ... psychiatric changes), high ... or if a primary hematologic ... #Workup #hematology