38 results
diagnosis treatment clinical hematology differential disease endocrinology orthopedics radiology rheumatology signs summary symptoms syndrome anatomy complications dermatology hemophagocytic hlh hypercalcemia
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... and formation of bone ... more (polystotic) bones ... pelvis, and long bones ... #diagnosis #management
Rheumatoid arthritis (RA): X-ray features • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... Peri-articular osteopenia (bones ... Radiology #Clinical #Pathophysiology
Hypercalcemia - Hormones and Pathophysiology Calcitriol: • Bones: Enhances mineralization • GI Tract: ↑ Ca2+
Calcitriol: • Bones ... PO4- PTH: • Bones ... : ↑ Bone resorption ... Calcitonin: • Bones ... : ↓ Bone resorption
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Pathophysiology of Menopause Organ System Changes: - CNS / Vasomotor Instability - Urogenital Mucosa - Cardiovascular - Bones #Pathophysiology #Menopause #Changes
Pathophysiology ... Cardiovascular - Bones ... #Pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
cause excessive bone ... MSK • Deformed bones ... Lytic lesions make bones ... of middle ear bones ... PagetsDisease #pathophysiology
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... Hypercalcemia #Malignancy #Pathophysiology ... Differential #Diagnosis #algorithm
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Diagnosis and Management ... - Accelerated Bone ... Formation: Hungy Bone ... Hypocalcemia #Diagnosis #Management ... #differential #algorithm
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... inflammation of the bones ... swelling of the bone ... • Bone and joint ... Rheumatology #diagnosis #management
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