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diagnosis hematology algorithm thrombocytopenia acidosis arteritis bruising cardiology conjugated elevatedmcv elevation endocarditis endocrinology erythematosus extravascular gca giantcell hemolysis hemolytic infectiousdiseases
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Chronic Disease (e.g ... #MCV #Classification ... #Hematology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... , hemolytic anemias ... miscellaneous causes ... #unconjugated #differential ... #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #differential #
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature - Differential ... Panhypopituitarism Treatment ... #ShortStature #Differential ... endocrinology #causes ... #pediatrics
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g ... #peds #pediatrics ... #diagnosis #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... - Compartment syndrome ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... #hematology
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