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diagnosis differential rheumatology management algorithm neurology signs symptoms barre classification complications hematology immunology lupus sle syndrome treatment acutelimbischemia agammaglobulinemia ali
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... antibiody -> Immune Complex ... > Incr Immune Complex ... Formation -> Vasculitis ... #HUV #Pathophysiology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... than females Guillain-Barre ... Pathophysiology ... walking to nearly complete
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings Ileus: Functional bowel "blockage", no peristalsis Mechanical Obstruction:
of bowel lumen Complete ... bowel-movements (suggests complete ... light-switch pain") with complete ... percussion • Nausea ... obstruction #sbo #ileus #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... Glomerulonephritis #Vasculitis
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... Leukocytoclastic Vasculitis ... (LCV), Immune complex ... nonpalpable #palpable #Causes ... Differential #Diagnosis #vasculitis
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Focal: Simple, Complex ... malformation, Aneurysm, Vasculitis ... Diagnosis #Algorithm #Causes
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... adhesion of IgA complexes ... Formation of immune complexes ... periumbilical region), nausea ... HenochScholeinPurpura #Pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... When to Consider Vasculitis ... tracts Immune Complex ... Vasculitis • ... tract, and often causes
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
antigen-antibody complexes ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... Signs #Symptoms #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Manifestations • Immune Complex ... Myopathy (Also caused ... Complications #pathophysiology
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