40 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... family history - Medications ... PLT in selected cases ... test, ANA (e.g., SLE ... Differential #Diagnosis #Causes
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
IV - Diffuse Proliferative ... Lupus #Nephritis #SLE ... Classification #Classes ... differential #diagnosis #management ... #nephrology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... • Special cases ... #rheumatology # ... levels #lupus #management
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... COVID19, CMV/EBV, HIV ... immobility • Critical ... Subacute to Chronic Causes ... tissue disorder, SLE
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... Usual therapeutic management ... #Summary #rheumatology
Possible Causes of Altered Urine Color 

Red 
    Foods: beets, blackberries, rhubarb
Possible Causes ... rhabdomyolysis); see ... indomethacin, IV ... cimetidine, IV ... Differential #Diagnosis #Nephrology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis, causes ... and management ... cryoglobulinemia vasculitis Clinical ... Cryoglobulinemia #Vasculitis #Rheumatology ... Cryoglobulinemic #Diagnosis #Management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... #treatment #management ... #rheumatology # ... nephrology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... to 1:1 F:M • Clinical ... Discontinuation of causal ... Positive in 60-80% of cases ... comparison #table #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... Scl-70 (in some cases ... body-like: - Neurologic ... Rods/rings: - HCV ... differential #diagnosis #rheumatology