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differential management algorithm dermatology injury anemia ascites eosinophilia leukemia liver mds myelodysplastic sweet thrombocytosis treatment workup aflp aki aplastic apml
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute ... agents to improve counts ... Management #treatment #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... - Differential Diagnosis ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... Absolute neutrophil count ... Hyperuricemia • Acute ... #differential #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Fatigue • Acute ... #Algorithm #Causes ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... Thrombocytosis): • Acute ... Myelodysplastic syndrome ... #Causes #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... white blood cell count ... translocation • Acute ... thrombocythemia • Acute ... #causes #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Lymphocytopenia DIAGNOSTIC ... T-cell count of ... chemotherapy) • Genetic syndromes ... #hematology #Differential ... #Causes #lymphocytopenia
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Differential Diagnosis ... Infiltrative disease • Acute ... #Algorithm #Hepatology ... #causes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... - Differential Diagnosis ... obstruction, HELLP Syndrome ... #Causes #Acute ... #algorithm #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... from low blood counts ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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