46 results
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
CHA2DS2VASc vs HAS-BLED ... for stroke risk and ... hypertension 1 A Abnormal ... Anticoagulation #AFib ... #Diagnosis #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Increased Requirement (e.g ... Liver Function ... • Rule out B12 and ... Liver Function ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Chronic Disease Normal ... Chronic Disease (e.g ... Renal Disease, Liver ... Reticulocytosis • Liver ... Algorithm #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Destruction • Abnormal ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... age • Monitor and ... #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
(record start and ... of information (e.g ... medications, Hidden OTC and ... vascular disorder (e.g ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
autoimmune disease (e.g ... dryness of the eyes and ... specific ANAs (e.g ... Liver biopsy findings ... Diagnosis #Algorithm #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
inflammation (eg ... been reported (eg ... of Hepatitis (eg ... Histology Findings (eg ... #Hepatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... inhibitory drugs e.g ... Nonspecific inhibitor e.g ... #differential #hematology