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diagnosis treatment differential syndrome blood criticalcare dermatology lupus neurology pharmacology sle summary symptoms abscess acquired activation algorithm als amyotrophic antinxp2
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Management • ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... Syndrome #Diagnosis #Management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
cases Clinical Signs ... years - May have signs ... symptoms of active pulmonary ... decreased reflexes Pathophysiology ... - Detection of AFB
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... cause ischemia and ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL and ... Special cases (e.g ... Measurement #SLE #rheumatology ... levels #lupus #management
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
- Intrauterine and ... both autologous and ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
, such as IL-1 and ... underlying disease (eg ... • Infection (eg ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... APML #diagnosis #management ... #hematology #oncology
Shock - Diagnosis and Management Summary • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Management Summary ... Full Set of Vital Signs ... telemetry, 12-Lead EKG ... Tamponade - Pulmonary ... Shock #Diagnosis #Management
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