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diagnosis algorithm cardiology treatment neurology syndrome rheumatology secondary chronic classification dermatology elevatedmcv elevation emesis endocarditis macrocytosis signs symptoms systemic thrombocytopenia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... • Secondary (e.g ... Normal RBCs • Acute ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Thrombocytosis): • Acute ... malignancies • Anemia ... inflammatory disorders (e.g ... #hematology #secondary
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... Iron Deficiency (Eg ... Other • e.g ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #differential #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Chronic Disease (e.g ... Classification #Differential ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g ... Marrow suppression (e.g ... Index > 3: • Acute ... Intrinsic RBC defects (e.g ... #anemia #differential
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Neutrophils - Differential ... Solid Tumour (e.g ... Polycythemia vera Acute ... #Hematology
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
(Ischemia) - Acute ... • Sickle Cell Anemia ... Septic Embolism (e.g ... Fat Embolism (e.g ... Mycotic Aneurysm (e.g
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Increased Requirement (e.g ... #elevatedMCV #Differential ... #Hematology
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