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diagnosis hematology causes anemia lymphadenopathy diffuse focal localized mcv bandemia cbc classification clinicopathology compared enlarged erythemas hemolytic hodgkins laboratory lymphoma
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Inflammatory / Infectious ... • Neoplastic (Leukemia ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... Pseudotumor - Infectious ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Diagnosis Algorithm ... • Kikuchi Disease ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... Infectious • ... • Lymphoma • Leukemia ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... Myelofibrosis Infectious ... disorders • Celiac disease ... #Causes #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... involved) • No leukemic ... #oncology #diagnosis ... #differential # ... hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Thalassemia • Lead ... Inflammation, Chronic Infection ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... extramedullary disease ... activity • ↓ LAP ... pain, bleeding, infections ... #Hematology #Oncology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... deficiency • Lead ... Macroangiopathic, Infections ... Non-megaloblastic: Liver disease ... Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... nucleotidase deficiency, lead ... inclusions - If infection ... #workup #hematology
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