18 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Liver disease, ... Bite Cell RBC: G6PD ... Cell RBC: Thalassemia ... Sickle Cell RBC ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Defects, Drugs, Liver ... anemia, Thalassemias ... Hypophostphatemia Laboratory ... Dehydrogenase ↑ - Peripheral ... Differential #Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... , Liver diseases ... , Liver diseases ... #differential #hematology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... sickle cell hepatic ... hepatomegaly and anemia ... Liver transplant ... Hepatobiliary #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Vasculature • Hepatic ... Congestion/CHF • Hepatic ... Malignancy, 1° PBC ... , Sickle Cell, VOD ... Acute #algorithm #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Findings in Hepatic ... disease, ALT and ... deficiency - Anemia ... #Hepatology #Laboratory
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral ... changes), high MCV anemia ... disease), HBsAg ... not required in all ... Causes #Workup #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Injury: • Hepatic ... • Hepatic artery ... breast CA, small cell ... fibrosis, Sickle cell ... diagnosis #algorithm #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... released in the peripheral ... Chronic kidney disease ... defects (e.g. sickle cell ... Production #Index #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... cytometry • Peripheral ... cells can indicate disease ... • Neutropenia, anemia ... workup #oncology #hematology