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diagnosis rheumatology differential management sle erythematosus algorithm classification systemic antibodies table acr2021 ana antinuclear arthritis associations autoantibodies dermatology diseases druginduced
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... ) • Systemic lupus ... Vasculitis: • ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... Vasculitis A group ... associated with PR3+ antibody ... associated with MPO+ antibody ... PR3 #Diagnosis #Rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... antibody), dsDNA ... Antiphospholipid Antibody ... glycoprotein I (ß2GP), Lupus ... Vasculitis: P-ANCA
Proposed treatment algorithm for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis #anca #vasculitis #treatment #algorithm #rheumatology #nephrology
Proposed treatment ... antineutrophil cytoplasmic antibody ... vasculitis # ... anca #vasculitis ... #rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Graves' disease c-ANCA ... - Vasculitis, e.g ... - Vasculitis, e.g ... disease Endomyseal antibody ... diagnosis #table #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... A Antinuclear Antibody ... (ANA) M Mucositis ... Pleuritis) H Hematologic ... sle #systemic #lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- ANCA specific ... inflammation Others: • Lupus ... Vasculitis: + MPO-ANCA ... such as systemic lupus ... differential #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... (C-ANCA): GPA > ... (P-ANCA): eGPA, ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... basement membrane; ANCA ... antineutrophil cytoplasmic antibody ... #Diagnosis #Rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
IMMUNOLOGIC CRITERIA - ANA ... - Anti-dsDNA antibody ... the presence of antibody ... Antiphospholipid antibody ... #Diagnosis #Rheumatology
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