8 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... femoral heads • Myopathy ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... hypothyroidism Pathophysiology ... Asymptomatic CK ... #pathophysiology ... #signs #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
tensile strength of muscle ... damage to nerves, muscles ... Diagnosis #signs #symptoms ... #msk #orthopedics ... #pathophysiology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... Hyperreflexia - Muscle ... - Radiation myelopathy ... , Scleroderma, Systemic ... differential #algorithm
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... • Conduction system ... Very high serum CK
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Classification #pathophysiology