24 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Weakness, Incr CK ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Schematic examples of the cause of acute mitral regurgitation. 
LV, left ventricle; PM, papillary mucle; SAM,
cause of acute mitral ... PM, papillary mucle ... ; SAM, systolic ... 2018-313373 #Mitral ... #Differential #Cardiology
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
Secondary Causes of Mitral ... cushion defects), Systemic ... rupture • Papillary muscle ... cardiomyopathy, Papillary muscle ... differential #diagnosis #cardiology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
Causes of mitral stenosis
Rheumatic heart disease
 - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... chordae Severe mitral ... one papillary muscle ... Secondary to systemic ... #differential #cardiology
Systolic Murmurs - Differential Diagnosis Algorithm
Benign / Flow / Hyperdynamic:
 • Pregnancy
 • Fever
 • Anemia
Supravalvular
Systolic Murmurs ... Marfan's Disease Mitral ... Regurgitation - Papillary Muscle ... Carcinoid #Systolic ... #Murmurs #Cardiology
Cardiac Findings in Sarcoidosis
Most Commonly Affected Sites:
 - LV free wall (esp. basal posterior wall)
 -
Aneurysm - Global systolic ... - Papillary muscle ... Abnormalities: - Mitral ... of leaflets - Mitral ... #Sarcoidosis #Cardiology
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
and Functional Mitral ... or LV papillary muscle ... - Secondary to systemic ... displacement of papillary muscles ... Differential #Diagnosis #Cardiology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... Hyperreflexia - Muscle ... equina- decreased muscle ... Infections: - Viral ... , Scleroderma, Systemic