21 results
diagnosis differential management causes oncology algorithm classification hemolysis infectiousdiseases listeria listeriosis microbiology monocytogenes abnormal abnormalities activation acute agglutinin aiha autoimmune
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology ... #anemia
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Anemia (AIHA) Treatment ... esp if severe disease ... azathioprine Cold ... Polyclonal: - Infection ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... • Symptoms of anemia ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... inclusions - If infection ... #Anemia #Differential ... Algorithm #workup #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic ... Causes: • Liver disease ... • AIHA: warm, cold ... drug induced • Infections ... classification #hematology
Listeriosis Summary - Listeria Monocytogenes Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming Risk
, motile, beta-hemolytic ... PPI use Food: Cold ... Pregnancy • CNS ... ) • CSF (CNS Infection ... infectiousdiseases #treatment
Listeriosis Summary - Listeria Monocytogenes Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming Risk
, motile, beta-hemolytic ... PPI use Food: Cold ... Pregnancy • CNS ... ) • CSF (CNS Infection ... infectiousdiseases #treatment
Acute and Chronic Causes of Dyspnea - Differential Diagnosis Pulmonary/Chest Wall: • Acute: Trauma, COPD exacerbation, Asthma
Acute: Trauma, COPD ... Chronic: Asthma, COPD ... Tamponade • Chronic: Anemia ... , Anaphylaxis, Infection ... hernia, Obesity CNS
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA, Cold ... Internal (RBC) - Infections ... Defects: Sickle cell anemia ... Differential #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease
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